Showing posts with label vaccine. Show all posts
Showing posts with label vaccine. Show all posts

Friday, July 12, 2019

Experimental HIV Vaccine By Johnson & Johnson To Begin Human Trials

Pharmaceutical company Johnson & Johnson will soon begin testing an experimental HIV vaccine in the U.S. and Europe sometime this year, according to Bloomberg News.


Pharmaceutical company Johnson & Johnson will soon begin testing an experimental HIV vaccine in the U.S. and Europe sometime this year, according to Bloomberg News.

The experimental vaccine, described as a “mosaic-based preventative immunization,” is made up of four components that target several strains the HIV virus.

The vaccine utilizes an altered cold virus to create a group of “mosaic” proteins that will elicit immune responses to a variety of strains.

Approximately 3,800 men who have sex with men are expected to take part in the trial expected to begin later this year. The participants will receive a series of six shots in four sessions.

Dan Barouch, a Harvard Medical School professor who has worked on the vaccine for years, told Bloomberg the J&J vaccine has provided protection in up to two-thirds of tested animals.

Results from the human trials are expected as soon as 2023.

Additionally, another version of the mosaic vaccine is currently being tested across five countries in southern Africa. Some 2,600 women are enrolled in that study called “Imbokodo.”

According to J&J, “Imbokodo” is the Zulu word for ‘rock’ which is part of a well-known proverb in South Africa that refers to the strength of women and their importance in the community.

Results from Imbokodo are expected in 2021.

Wednesday, February 18, 2015

Science: New Anti-HIV Drug Could Work As Unconventional Vaccine


Exciting news today from Science Daily - a new anti-HIV drug candidate appears so potent it could work as an unconventional vaccine against the disease:

The study shows that the new drug candidate blocks every strain of HIV-1, HIV-2 and SIV (simian immunodeficiency virus) that has been isolated from humans or rhesus macaques, including the hardest-to-stop variants. It also protects against much-higher doses of virus than occur in most human transmission and does so for at least eight months after injection.

"Our compound is the broadest and most potent entry inhibitor described so far," said Michael Farzan, a TSRI professor who led the effort. "Unlike antibodies, which fail to neutralize a large fraction of HIV-1 strains, our protein has been effective against all strains tested, raising the possibility it could offer an effective HIV vaccine alternative."

Read more at Science Daily.